Bone marrow chimera can have various implications depending on the context. In the case of allogeneic HSCT, where the donor and recipient are not genetically identical, the procedure is often performed to treat hematological malignancies, immune deficiencies, or certain genetic disorders. The presence of a bone marrow chimera indicates successful engraftment of donor cells and is generally associated with improved outcomes in terms of disease remission or immune reconstitution.
Bone marrow chimeras can be detected and monitored through various techniques, such as flow cytometry or polymerase chain reaction (PCR), which can identify the presence and proportion of donor and recipient cells in the blood or bone marrow.
